- Every HP upgrade is now worth 2 soul hearts. Certain items consider Quality for picking what item to spawn, allowing better items to spawn under certain conditions, UNLOCK: Unlock this item by defeating The Beast as Tainted Lost, Spawns a special set of spikes in the Devil Room, Taking damage from the spikes has a chance to spawn a reward, UNLOCK: Unlock this item by defeating The Beast as Tainted Judas, When picked up, this gives you 9 orbital flies, Each time a fly blocks an enemy shot, it will turn into a blue fly and attack nearby enemies, leaving you with one less orbital, Every room clear gives you +1 orbital fly, up to a maximum of 9, UNLOCK: Unlock this item by defeating The Beast as Tainted Blue Baby, Gives you +0.25 Damage Up for every broken heart you have, Every hit of damage that would kill you, instead adds 2 more broken hearts and deal 40 damage to all enemies in the room, UNLOCK: Unlock this item by defeating The Beast as Tainted Eve, Every time you take damage, you gain a Speed Up and a Tears Up, The stat increases start small, and scale up each time you take damage (+0.25 Tears Up for the first hit, +0.75 Tears Up for the 6th hit), The effect maxes out at +3 Tears Up and +1 Speed Up after taking damage 6 times. Spikes and Curse Rooms no longer deal damage, Sharp Plug becomes useless with this item, due to how damage is prevented on Isaac's body, REPENTANCE - Isaac's Heart has a charge attack, which pushes enemies away and fires blood tears in all directions. It will also sometimes randomly drop bombs. Any Tarot card or rune on the floor or current held when picking this item up will change into a pill, Dice Shard counts as a card and will be converted, UNLOCK: Unlock this item by picking up 2 of the following items: Roid Rage, The Virus, Growth Hormones, Experimental Treatment or Speed Ball, * shop room pool, shop item pool, brown, purple, * boss room pool, boss room item, red, wedge, purple, triangle, The above stats only apply to tears fired from Isaac's left eye or with a 50% chance if you have an item which causes you to fire from a single source only, * boss room pool, boss room item, red, blob, circle, spot, * boss room pool, boss room item, grey, gray, Enemies touching placed bombs take 16 damage, Gives all bombs a burning effect when they explode, leaving fire on the floor which deals 22 damage to enemies, REPENTANCE - Hot Bombs now have greatly increased contact damage (increased from 1 to 16), and passively grants Isaac immunity to fire, * item room, treasure room, item room pool, fire, orange, flame, face, Isaac's tears now set enemies on fire, leaving a damage over time effect that does 4 or 6 damage per tick, There is a chance that tears that hit enemies will explode, leaving a small fire on the floor that damages enemies, Exploding tears deal damage * 2 + 22 per tick, The chance for tears to explode is affected by your luck stat and at +13 Luck it will activate every time, * item room, treasure room, item room pool, fire, flame, orange, back, ball, burning, When picked up, and at the start of each floor this rerolls all your current items, giving you a new item to replace each of the ones you had, Also rerolls all your stats at the same time, giving a random flat modifier that changes each time, Doesn't affect important items such as Polaroid, Negative and Key Pieces, UNLOCK: Unlock this item by beating Boss Rush with Lazarus, * secret room pool, mondrian, painting, yellow, blue, red, white, Tears now have a chance to apply the fear effect to enemies, which causes them to run away from Isaac, The chance to fear enemies is affected by your luck stat and at +20 Luck it will activate every time, An item only found in the devil room pool (Note: The Fallen boss pulls items from the Devil Room Pool), * devil pool, devil room pool, devil deal, grey, gray, fist, glow, Immunity to all floor curses (e.g. Based on the Steam Workshop mod created by Ratlah, UNLOCK: Unlock this item by sleeping in 10 different beds, When used, this item will sacrifice up to 2 of your familiars (chosen at random), and spawn a random Devil Room item for each familar sacrificed this way, In addition to the familiars, any blue flies or spiders will be converted to 1 coin each, If Guardian Angel, Sworn Protector, or Seraphim is sacrificed, Satan will be extra happy and reward you with 2 black hearts, Incubus won't be sacrificed if you're playing as Lilith, If used while you have no familiar, this item will do nothing and won't consume the item, Added as part of the Afterbirth+ Booster Pack #5. or the path they take (My Reflection, Tiny Planet etc. Speed Up will be +0.3 instead of +0.15. Spawns another Vurp! Similar to Explosive Diarrhea but with poop, Retro Vision - Pixelates the screen for a few seconds, obscuring your vision. The pick-ups which are NOT items, are the Pills, Tarot Cards and Trinkets. For everything it increases by 1 coin * the number of purchases, The max price of an item is always 99c with this item, Works with Keeper's Box and the Member Card extra shop, Most spider enemies no longer target or deal contact damage to Isaac, This is very similar to a Skatole for spiders instead of flies, Continuously firing or charging tears for 3 seconds causes Isaac to fart and drop a Butt Bomb, Only 1 Butt Bomb can be dropped per charge, so you'll need to stop firing then start again to drop another one, Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time, *, yfront, y-front, underpants, underwear, white, grey, gray, no 2, number two, number 2, no two, Transforms Isaac's tears into a wide arc shape which doubles their size and hitbox, *, flat, white, grey, gray, blue, drip, water, eyes, This item turns all doors that require a key into doors which need a coin to enter instead, This affects shops, item rooms, libraries, double locked doors, key blocks, chests and other key doors, Changes the appearance of doors and objects that this item works on to show a coin slot instead of a keyhole, Item Pool: Shop, Greed Mode Item Room, Greed Mode Shop, *, grey, gray, metal, slot, rectangle, silver, Gives you a random item at the start of your next run (You need to start a fresh run to receive the item), Important progression items such as Key Pieces or the Mom's Shovel pieces cannot be given by Eden's Blessing, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Eden, When used, can be thrown at enemies to capture them (similar to a Pok Ball), After capturing an enemy, the next use of the Friendly Ball will re-spawn the same enemy as a friendly companion which will attack other enemies, The companion will persist between rooms and floors until it dies by taking enough damage, Walking over the thrown ball after capturing an enemy will immediately recharge it, *, pokemon, grey, gray, blue, deathstar, circle, When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head, Luck-based items such as Holy Light are applied to each tear individually, Gives Isaac a familiar Gurdy that will charge around the room dealing contact damage to enemies, The Gurdy is charged by holding down the fire button and letting go. debug 4 - +40 damage to the hero's tears. the lost item pool, white, blue, cross, jar, Gives Isaac an eternal heart and the ability to fly, UNLOCK: Unlock this item by beating the Chest with Blue Baby, * golden chest pool, gold chest pool, blue head, the lost item pool, dead, ball, Upon taking damage, Isaac will fart a few times, causing all enemies in close proximity to become poisoned and leaving a gas cloud behind, Black Bean deals your tear damage for 6 ticks, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, the lost item pool, kidney, grey, gray, Allows Isaac to fly while the White Pony is held, While held, sets your speed stat to 1.5 if it isn't already that high. Upon use, this item summons a ghost near Isaac that will follow him around. Basement 1, Cathedral, Sheol etc. The actual explosion deals flat 60 damage, Pestilence (Green) - Poisons the enemy it attacks, Famine (Brown) - Applies a slowing effect, Death (Black) - Deals x4 damage instead of x2, UNLOCK: Unlock this trinket by defeating Isaac, ?? now allows the player to influence the teleport direction (using the direction Isaac is moving upon activating the item), * item room, treasure room, item room pool, blue remote, robot, When used as the Keeper, one coin HP is restored, Has a chance to drop from the Super Lust miniboss fight, Item Pool: Item Room, Super Lust Miniboss, * item room, treasure room, item room pool, the lost item pool, maggy, starting, After entering a Planetarium the chance goes back to 1%. Red chests), Can be used in a shop to duplicate pickups which have not yet been purchased, and take the duplicate pickup for free, UNLOCK: Unlock this item by defeating Greedier Mode with Isaac, When used, Void will consume any pedestal items in the current room, If an active item is consumed, its effect will be added to Void's effect when used, allowing you to consume multiple items and combine their effects, If a passive item is consumed, you gain a small stat upgrade to a random stat, Possible stat changes include: +1.0 flat damage, +0.5 tears, +0.2 speed, +0.2 shot speed, +0.5 range, +1.0 luck, Void does not work on devil deal or shop items unless they have been bought first, Using Void to absorb items in Boss Rush or Challenge Rooms counts as taking the items and will cause the encounter to start, Using Void on one time use items such as Mama Mega or Diplopia will cause their effect to instantly trigger and will not give you further uses through activating Void again, UNLOCK: Unlock this item by beating Delirium in The Void floor with Apollyon, Upon use, this item freezes all enemies in the room until you press the fire button again or 30 seconds passes (whichever happens first), Unlike other active items, bosses are not immune to this effect, Touching a frozen enemy will still hurt you, This item doesn not affect troll bombs - they will still explode, Upon use, the Smelter will destroy your currently held trinket and give you the effect permanently, allowing you to stack up lots of different trinket effects, Holding the Smelter increases the chance for a trinket to drop. the lost item pool, white, black, Each time you take damage, you gain a damage up which lasts for the rest of the floor and turn a darker red colour each time, After taking 6 hits Bloody Lust doesn't give you any further damage increases, Damage given for each hit increases as follows: +0.5, +0.7, +0.9, +1.1, +1.3, +1.5, REPENTANCE - The damage increments have changed slightly, UNLOCK: Unlock this item by beating the Isaac boss with Samson, * item room, treasure room, item room pool, the lost item pool, starting, red, blood, drop, Upon use, reveals the map and drops either a soul heart or a random card/rune (50% chance for each), It reveals the location of the secret room, however it doesn't reveal the Super secret room, Has a chance to drop from playing a fortune machine. This means if you roll into The Lost, changing back to another character will leave you with only 1/2 of a soul heart, Cannot turn you into a character that isn't unlocked yet, Also includes Lazarus II (Lazarus' revived form) and Dark Judas (effect of Judas' Shadow), It's also possible that this item will pick the same character, making it seem like nothing happened, *, grey, gray, black, remote, zapper, changer, building, A one time use item that when used will explode all objects (i.e. REPENTANCE - White Pony's charge time has been reduced to 2 (from 6). After taking two hits, the fire will be extinguished, The Book can be held at the same time as another active item. Drop a LIKE and nice l. If it does, it will drop a random trinket, coin, heart and key, The Walnut trinket is destroyed once the effect activates, Causes any orbitals you have to stop moving while held, Stops shooting familiars from moving (including Lilith's Incubus), Some familiars with irregular movement are not affected by Duct Tape, such as Abel, BBF, Bumbo, Guppy's Hair Ball, Lil Gurdy, Punching Bag, Robo-Baby 2.0, Succubus, *, grey, gray, tp, toilet, paper, roll, silver, While held, shops will now appear on the womb floors (The Womb, Utero and Scarred Womb), UNLOCK: Unlock this item by defeating Delirium in The Void floor with Cain, While held, item rooms now appear on the womb floors (The Womb, Utero and Scarred Womb), REPENTANCE - Causes item rooms to appear on Corpse floors, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Samson, While held, restock boxes will always spawn in item rooms, *, cent, money, cash, coin, pixel, blue, green, p2w, Upon entering a room with enemies, spawns a Red Locust which detonates upon impact with enemies, dealing double tear damage for the impact of the Locust and 60 damage for the explosion, Can be dangerous as the fly will target the nearest enemy, which can be close enough to catch Isaac in its blast radius, UNLOCK: Unlock this trinket by defeating Isaac in the Cathedral as Apollyon, At the start of each new hostile room you spawn a green attack fly, which will target a nearby enemy, deal double your tear damage and then poison them, UNLOCK: Unlock this item by beating Satan with Apollyon, At the start of each new hostile room you spawn a yellow attack fly, which will target a nearby enemy, deal double your tear damage and apply a slowing effect to it, UNLOCK: Unlock this trinket by defeating ??? If picked up by Cain, it shoots blood tears and the damage becomes increased to 5 (instead of the usual 3.5), UNLOCK: Unlock this item by beating the Dark Room with Cain, * golden chest pool, gold chest pool, item room, treasure room, item room pool, follower, everyone knows it's abel, brown, grey, gray, dead, head, grey, green cain and abel cain & abel, UNLOCK: Unlock this item by beating Challenge #14 (It's in the Cards), * item room, treasure room, item room pool, bloody, silver, grey, gray, sharp, Item Pool: Item Room, Secret Room, Bomb Beggar, * secret room pool, item room, treasure room, item room pool, smile, face, grinning, doitfgt, REPENTANCE - The list of possible tear effects was updated in Repentance, to include all missing and new ones, * item room, treasure room, item room pool, pink note, money, cash, three dollar bill, I don't intend in publishing it anywhere when I finish it, but I do want to know opinions and what would you change. Based on the Steam Workshop mod created by electoon and Erfly, *, dark side of the moon, rainbow, red, yellow, green, white, triangle, pink floyd, thought, Replaces Isaac's tears with eyeballs that can bounce off of each other, Issac's tears are no longer limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle, Added as part of the Afterbirth+ Booster Pack #3. Battery - 6.6% chance, Also adds a 20% chance to spawn a fly if the original drop was a coin, UNLOCK: Unlock this trinket by defeating Isaac, ?? One of the best parts of the Binding of Isaac is the huge number of item interactions and synergies you can get by combining certain items, however they don't always work as expected. Cannot be rerolled by 4-pip dice rooms and Spindown Dice, Clearing a room will spawn an extra reward, however only one can be picked up - the other one will disappear, UNLOCK: Unlock this item by defeating the The Beast as Isaac, Every half red heart you pick up gives a small but permanent stat increase, Randomly picks between +0.10 Damage Up, +0.05 Tears Up, +0.15 Range Up, +0.02 Speed Up, +0.1 Luck Up, +0.02 Shot Speed Up per half red heart, UNLOCK: Unlock this item by defeating The Beast as Magdalene, This item causes Devil deals to cost money instead of hearts, and shop items to cost hearts instead of money, Shop items cost heart containers, and pickups have spikes around them, The Devil deal conversion rate is 1 heart container to 15 coins, Devil deal items can be on discount similar to the shop, making it 1 heart container = 7 coins instead, UNLOCK: Unlock this item by defeating The Beast as Cain, Every time you enter a devil room and choose not to take an item, you get +1 Damage Up upon entering the next floor, The effect is shown via a cross above Isaac's head. Items are an integral part of gameplay in The Binding of Isaac. Tears continue to fire from your left eye, The laser deals damage equal to 1/7th of your tear damage, but very rapidly, The laser can apply status effects (e.g. Chests now have a 50/50 chance to either pay out with extra consumables or nothing/an enemy, UNLOCK: Unlock this trinket by beating Challenge #26 (I Rule), Tears have a stronger knockback effect while this trinket is held. Just select an item from each of the two selection boxes below to see a description of . Does not apply to locked chests, * item room, treasure room, item room pool, red, horse shoe, Reveals the entire map for every floor except the secret room locations, Does not show the icons for any unexplored rooms, Can still help you to guess which direction the boss room is in, due to the fact that the Boss Room is usually in the room furthest away from the first room, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, * item room, treasure room, item room pool, white, purple, Gives Isaac the ability to fly and spectral tears, * devil pool, devil room pool, devil deal, red, crescent, moon, drop, black, Creates 5 beams of light from the sky that deal damage equal to your tear damage + 20 to any enemies which come into contact with them, The beams have a high chance to spawn on top of enemies where possible, * item room, treasure room, item room pool, feather, white, arrow, Upon death, you respawn in the previous room as Blue Baby with three Soul hearts, This is a one time use item and all new heart containers will be soul hearts, Can be used to unlock some of Blue Baby's secrets before having the character available, * item room, treasure room, item room pool, black, grey, gray, extra life, egypt, grey, gray, Upon taking damage, you have a 20% chance to gain an invulnerability shield for 7 seconds, The chance to gain a shield is affected by your luck stat and at +27 Luck it will activate every time, UNLOCK: Unlock this item by beating the Chest with Maggy, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, At +0 Luck theres a ~2.5% chance for this effect to activate, The size of the rift scales with your tear damage, In Antibirth this item was called Oculus Rift, A familiar boil that randomly fires bursts of tears, similar to the Boil enemy, A familiar baby that fires tears which have a chance to freeze or petrify enemies, When used, rerolls all items in the room into another random item from the current room's item pool, however the item also has a 30% chance to disappear, The chance associated with this item does NOT scale with your Luck stat - it's always 30%, In the game files this item is called 'Florians Dice', which is a reference to the Eternal update for the original Binding of Isaac game, which changed the D6 to act as this item does. While held there is a small chance when using a tarot card or pill that a copy of it will be dropped on the floor next to you, +0.2 Damage Up for each 'evil' item you have, Items classed as evil in this case are Black Candle, Ceremonial Robes, Abaddon, Goat Head, Match Book, Missing Page 2, Safety Pin, UNLOCK: Unlock this item by beating Greed Mode with Eve, Invincibility lasts longer after getting hit (Increased i-frames), This makes it possible to use the Blood Donation machine twice from one hit of damage, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Samson, *, bandana, sling, white, knot, blindfold, +15% chance to get a double item room to spawn on the next floor, If the effect activates, two items spawn in your item room, however only one can be taken (Same effect as the More Options item), The chance doubles to +30% with the effect from Mom's Box, Automatically opens all shop room doors for free, UNLOCK: Unlock this trinket by donating 666 coins to the Greed Donation Machine, UNLOCK: Keeper starts with this trinket after beating Satan with Keeper, Forces the Greed and Super Greed mini bosses to no longer appear in shops or secret rooms, Holding Rib of Greed increase your chance to receive coin drops, UNLOCK: Unlock this trinket by beating Ultra Greed with Keeper, Donating to a Donation Machine has a chance to heal Isaac for a full red heart or spawn a Beggar, UNLOCK: Unlock this item by beating The Lamb boss with Keeper, Destroying poops now gives you a blue fly, While held, you heal for half a red heart every time you use a key to open a door or golden chest, Changes all half red hearts into full hearts, Hearts dropped from Tainted Magdalene's mechanic will be always full red hearts, *, red, brown, grey, gray, necklace, moms locket, mom locket, While this trinket is held you have a significantly lower chance to find spacebar/active items, It will cause passive items to spawn except when the game cannot generate any more passive items and will then instead choose spacebar/active items, Some hard coded spacebar items from bosses and mini-bosses (i.e. UNLOCK: Unlock this trinket by collecting three of the following in the same run: Magic 8 Ball, Tiny Planet, Crystal Ball, Star of Bethlehem or any of the Astrology-related items (e.g. When used, this item will rewind time and put you back in the previous room, in the same state you were in at that moment, This means any damage taken or consumables used in the current room will be reset back to the previous state, Can be used to check the contents of an Item Room without affecting Planetarium spawn chances, Glowing Hour Glass has no cooldown, but can only be used 3 times per floor (as of 1.7.9 update), Recharge time: None (Max 3 use per floor), Item Pool: Item Room, Shop, Greed Mode Item Room, * hourglass, hour glass, egg, timer, blue, brown Glowing Hourglass, Gives Isaac a large white halo around him, that deals a bit of damage to any enemies in contact with the ring, Every time an enemy bullet enters the ring, there is a chance it will reflect a homing tear back at the enemy, Coins have a 10% chance to be replaced with Sack.